Name :
KLF6 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KLF6 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, human placenta tissue, mouse colon tissue, mouse testis tissue, mouse thymus tissue, PC-3 cells. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 42-45kd
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
B cell derived protein 1 antibody; COPEB antibody; CPBP antibody; DKFZp686N0199 antibody; GBF antibody; KLF6 antibody; Krueppel like factor 6 antibody; Kruppel like factor 6 antibody; PAC1 antibody; Proto oncogene BCD1 antibody; ST12 antibody; Transcription factor Zf9 antibody; ZF9 antibody
Immunogen :
Human KLF6 Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KLF6 recombinant protein (Accession Number: NM_001008490). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
KLF6(krupple-like factor 6) is a zinc finger transcription factor and tumor suppressor with biological activities and transcriptional targets in growing range. It is highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. One key target gene of KLF6 in endoglin, which is a homodimeric cell membrane glycoprotein and TGF-β auxiliary receptor, owns a pro-angiogenic role in endothelial cells and is also involved in malignant progression. Also KLF6 induces apoptosis in prostate cancer cells through upregulation of ATF3. KLF6 was normal detected as a 46kDa protein, which is larger than translation product(32kDa), because of post-translational modification including both phosphorylation and glycosylation. This antibody raise against the full length of KLF6 gene of human origin, and can recognize both of KLF6, included KLF6(~32kDa), p-KLF6(~35-46kDa). Otherwise, there may be a non-specific band(50kDa) showed in detection
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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