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Name :
KLF7 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KLF7 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Positive IP detected in K-562 cells. Observed molecular weight by Western-blot: 33 kDa

Tested applications :
ELISA, WB, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
KLF7 antibody; Krueppel like factor 7 antibody; UKLF antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of KLF7 recombinant protein (Accession Number: XM_017005164). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:1000

Background :
KLF7, also named as UKLF, is a 302 amino acid protein, which contains three C2H2-type zinc fingers and belongs to the krueppel C2H2-type zinc-finger protein family. KLF7 is ubiquitous and highly expressed in brain and spinal cord in the adult, and in kidney and brain in the embryo. KLF7 as a transcriptional activator localizes in the nucleus and binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence.

References :
Gao Y, Liu XF, Lu XC, Ma C, Cao J, Fan L. Protective effects of atorvastatin against oxidized LDL-induced downregulation of KLF expression in EA.hy926 cells. International journal of molecular medicine. 30(2):330-6. 2012.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel