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Name :
KLHL2 Polyclonal Antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Polyclonal antibody to KLHL2

Tested applications :
WB

Species reactivity :
Human

Alternative names :
KLHL2 antibody; ABP-KELCH antibody; MAV antibody; MAYVEN antibody; kelch-like protein 2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthetic Peptide of human KLHL2

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide, pH7.3.

Storage instructions :
Store at 4℃. Avoid freeze / thaw cycles.

Applications :
WB 1:500 – 1:1000

Background :
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel