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Name :
KLK3/PSA antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KLK3/PSA Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human prostate cancer tissue.

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human; other species not tested.

Alternative names :
APS antibody; Gamma seminoprotein antibody; hK3 antibody; Kallikrein 3 antibody; kallikrein related peptidase 3 antibody; KLK2A1 antibody; KLK3 antibody; P 30 antigen antibody; Prostate specific antigen antibody; PSA antibody; Semenogelase antibody; Seminin antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of KLK3/PSA recombinant protein (Accession Number: NM_001648). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200

Background :
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. kallikrein-related peptidase 3, which is also called PSA (prostate-specific antigen) in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. KLK3 has 5 isoforms produced by alternative splicing.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel