Name :
KLRG1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KLRG1 Rabbit Polyclonal antibody. Positive WB detected in human blood tissue, Raji cells. Positive IHC detected in human breast cancer. Observed molecular weight by Western-blot: 60 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
human; other species not tested.
Alternative names :
KLRG1 antibody; MAFA L antibody; 2F1 antibody; MAFA LIKE antibody; MAFA 2F1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KLRG1 recombinant protein (Accession Number: NM_001329099). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200
Background :
KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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