Name :
KMT5C Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to KMT5C
Tested applications :
WB
Species reactivity :
Human, Mouse, Rat
Alternative names :
KMT5C antibody; SUV420H2 antibody; Suv4-20h2 antibody; lysine methyltransferase 5C antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human KMT5C (NP_116090.2).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Histone methyltransferase that specifically trimethylates ‘Lys-20’ of histone H4. H4 ‘Lys-20’ trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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