Name :
KPNA2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KPNA2 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human colon cancer tissue. Positive WB detected in HepG2 cells, Jurkat cells, mouse heart tissue, Raji cells. Observed molecular weight by Western-blot: 55-58 kDa
Tested applications :
ELISA, WB, IF, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Importin subunit alpha 2 antibody; IPOA1 antibody; Karyopherin subunit alpha 2 antibody; KPNA2 antibody; QIP2 antibody; RAG cohort protein 1 antibody; RCH1 antibody; SRP1 antibody; SRP1 alpha antibody; SRP1alpha antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KPNA2 recombinant protein (Accession Number: NM_002266). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200
Background :
KPNA2 represents karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
References :
Wang CI, Chien KY, Wang CL. Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer. Molecular & cellular proteomics : MCP. 11(11):1105-22. 2012. Wang CI, Wang CL, Wu YC. Quantitative proteomics reveals a novel role of karyopherin alpha 2 in cell migration through the regulation of vimentin-pErk protein complex levels in lung cancer. Journal of proteome research. 14(4):1739-51. 2015. Yoshitake K, Tanaka S, Mogushi K. Importin-α1 as a novel prognostic target for hepatocellular carcinoma. Annals of surgical oncology. 18(7):2093-103. 2011. Wang CI, Wang CL, Wang CW. Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome. International journal of cancer. 128(10):2364-72. 2011.
Related websites: https://www.medchemexpress.com/antibodies.html
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