Name :
KRAS antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KRAS Mouse Monoclonal antibody. Positive FC detected in HeLa cells. Positive IHC detected in human lung cancer tissue, human colon cancer tissue. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 21 kDa
Tested applications :
ELISA, WB, IHC, FC
Species reactivity :
Human; other species not tested.
Alternative names :
C K RAS antibody; c Ki ras antibody; GTPase KRas antibody; K Ras 2 antibody; K RAS2A antibody; K RAS2B antibody; K RAS4A antibody; K RAS4B antibody; KI RAS antibody; KRAS antibody; KRAS1 antibody; KRAS2 antibody; KRAS2A antibody; KRAS2B antibody; KRAS2B speicifc antibody; Krasa antibody; Krasb antibody; NS3 antibody; RASK2 antibody
Immunogen :
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of KRAS recombinant protein (Accession Number: XM_011520653). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5′ non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. KRAS has two isoforms, a and b.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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