Name :
LAP3 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LAP3 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HepG2 cells, mouse heart tissue, SH-SY5Y cells. Positive IHC detected in human gliomas tissue. Observed molecular weight by Western-blot: 56kd
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Cytosol aminopeptidase antibody; LAP antibody; LAP 3 antibody; LAP3 antibody; LAPEP antibody; leucine aminopeptidase 3 antibody; Leucyl aminopeptidase antibody; PEPS antibody; Peptidase S antibody; Proline aminopeptidase antibody; Prolyl aminopeptidase antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LAP3 recombinant protein (Accession Number: NM_015907). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
LAP3(Leucine aminopeptidase 3) is also named as LAPEP, PEPS(peptidase S) and belongs to the peptidase M17 family. It can catalyzes the removal of unsubstituted N-terminal amino-acids from various peptides and be presumably involved in the processing end regular turnover of intracellular proteins. PEPS is found in a wide variety of tissues and cultured cells but not in red cells and skin. The enzyme can utilize several di-, tri-, and tetrapeptides as substrates and is the slowest migrating of the peptidases after electrophoresis.(PMID:689684).
References :
Zhu Z, Xu W, Dai J. The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis. The international journal of biochemistry & cell biology. 45(3):571-82. 2013. Huang S, Cui Y, Guo X. 2,2′,4,4′-Tetrabromodiphenyl ether disrupts spermatogenesis, impairs mitochondrial function and induces apoptosis of early leptotene spermatocytes in rats. Reproductive toxicology (Elmsford, N.Y.). 51:114-24. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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