Name :
LARS2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LARS2 Rabbit Polyclonal antibody. Positive IP detected in Jurkat cells. Positive WB detected in HepG2 cells, Jurkat cells, MCF7 cells. Observed molecular weight by Western-blot: 102 kDa
Tested applications :
ELISA, WB, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
KIAA0028 antibody; LARS2 antibody; Leucine tRNA ligase antibody; LEURS antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LARS2 recombinant protein (Accession Number: NM_015340). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000
Background :
LARS2 (Probable leucine–tRNA ligase, mitochondrial) is also named as mitochondrial LEURS. The deduced 903-amino acid protein has an N-terminal mitochondrial targeting signal that is cleaved after residue 39. LARS2 has characteristics of a class I aminoacyl-tRNA synthetase, including a classical Rossmann fold. It belongs to the class-I aminoacyl-tRNA synthetase family.
References :
Perli E, Giordano C, Pisano A. The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells. EMBO molecular medicine. 6(2):169-82. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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