Name :
LAS1L antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LAS1L Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive WB detected in HEK-293 cells, COLO 320 cells, HeLa cells, HepG2 cells, PC-3 cells. Positive IP detected in HEK-293 cells. Observed molecular weight by Western-blot: 83 kDa,70-75 kDa
Tested applications :
ELISA, WB, IP, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
dJ475B7.2 antibody; FLJ12525 antibody; LAS1 like (S. cerevisiae) antibody; LAS1L antibody; Protein LAS1 homolog antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LAS1L recombinant protein (Accession Number: NM_031206). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:500-1:5000IF: 1:20-1:200
Background :
LAS1L is a nucleolar protein required for the synthesis of the 60S ribosomal subunit and maturation of the 28S rRNA. LAS1L interacts with PELP1, TEX10, and WDR18, along with NOL9 and SENP3, to form a novel nucleolar complex that cofractionates with the 60S preribosomal subunit.
References :
Fanis P, Gillemans N, Aghajanirefah A. Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. Molecular & cellular proteomics : MCP. 11(11):1263-73. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
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