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Name :
liver Arginase antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
liver Arginase Mouse Monoclonal antibody. Positive IHC detected in human liver tissue, human liver cancer tissue. Positive WB detected in HepG2 cells. Observed molecular weight by Western-blot: 36 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
Arginase 1 antibody; liver Arginase antibody; Liver type arginase antibody

Immunogen :
Human ARG1 Recombinant protein (His tag)

Isotype :
Mouse IgG1

Preparation :
This antibody was obtained by immunization of liver Arginase recombinant protein (Accession Number: BC005321). Purification method: Protein G purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200

Background :
Liver arginase(Arginase-1) belongs to the arginase family. Hepatic arginase 1 is closely associated with alternative macrophage activation(PMID:12098359) and Arg1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel