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Name :
LRRC52 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LRRC52 Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 45 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
FLJ25811 antibody; LRRC52 antibody

Immunogen :
Human LRRC52 Recombinant protein (His tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LRRC52 recombinant protein (Accession Number: NM_001005214). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000

Background :
LRRC52 (leucine-rich repeat-containing protein 52) belongs to the gamma family of the BK channel accessory subunits, which potentially regulate the channel’s gating properties (PMID: 22547800). It is dominantly expressed in testis and skeletal muscle, with much lower expression in several other tissues including placenta, kidney, lung, and some glands. LRRC52 has been reported as a Slo3 auxiliary subunit that helps define the specific alkalization dependence of KSper activation. LRRC52 has a calcular molecular weight of 35 kDa. This polyclonal antibody raised against 24-244aa of human LRRC52 reveals a band of 45 kDa, which is consistent with the molecular weight of glycosylated form of LRRC52 (PMID: 22084117).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel