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Name :
LYVE1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LYVE1 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 60 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human; other species not tested.

Alternative names :
CRSBP 1 antibody; CRSBP1 antibody; HAR antibody; Hyaluronic acid receptor antibody; LYVE 1 antibody; LYVE1 antibody; XLKD1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LYVE1 recombinant protein (Accession Number: NM_006691). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
LYVE1 is a 322-amino acid type-I integral membrane glycoprotein primarily expressed on lymphatic endothelial cells. LYVE1 is a CD44 homologue. It acts as a receptor and binds to both soluble and immobilized hyaluronan. LYVE1 may function in lymphatic hyaluronan transport and have a role in tumor metastasis.

References :
Nakamura R, Sugano M, Sone Y, Sakabe K, Itoh T, Kiyono M. Establishment and characterization of a human lymphatic endothelial cell line. Biological & pharmaceutical bulletin. 37(4):683-7. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel