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Name :
MAN1A2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MAN1A2 Rabbit Polyclonal antibody. Positive WB detected in human placenta tissue. Positive IHC detected in human placenta tissue, human heart tissue, human lung tissue, human ovary tissue. Observed molecular weight by Western-blot: 73kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
Alpha 1 antibody; 2 mannosidase IB antibody; MAN1A2 antibody; MAN1B antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MAN1A2 recombinant protein (Accession Number: NM_006699). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200

Background :
The first group or Class I mannosidase is comprised of α1–2 mannosidases from mammals and yeast with encoded polypeptides of 65–75 kDa. Most of them are Ca2+-dependent enzymes located in the ER and/or Golgi which are inhibited by substrate mimics like kifunensine and deoxymannojirimycin. Their specificity is restricted to α(1–2) linkages, and they are mostly inactive towards artificial substrates like arylmannosides(PMID:10207175).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel