Name :
MCF2L Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to MCF2L
Tested applications :
WB
Species reactivity :
Human, Mouse
Alternative names :
MCF2L antibody; ARHGEF14 antibody; DBS antibody; OST antibody; guanine nucleotide exchange factor DBS antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 850-980 of human MCF2L (NP_079255.4).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:1000 – 1:4000
Background :
Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.; Isoform 3: Does not catalyze guanine nucleotide exchange on CDC42.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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