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Name :
MCM5 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MCM5 Rabbit Polyclonal antibody. Positive IHC detected in human lymphoma tissue. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells, A375 cells, HeLa cells, mouse thymus tissue. Observed molecular weight by Western-blot: 82kd

Tested applications :
ELISA, WB, IHC, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
CDC46 antibody; CDC46 homolog antibody; MCM5 antibody; P1 CDC46 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MCM5 recombinant protein (Accession Number: NM_006739). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
Minichromosome maintenance, S. Cerevisiae, homolog of 5(MCM5), one component of the complex of MCM2-7, which is the putative replicative essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The MCM complex form a hexameric ring through the interaction surfaces of two neighboring subunits.

References :
Liu YZ, Jiang YY, Wang BS. A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens. Cancer cytopathology. 122(11):833-41. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel