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Name :
MED31 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MED31 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, human brain tissue. Observed molecular weight by Western-blot: 16kd

Tested applications :
ELISA, WB

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
3110004H13Rik antibody; CGI 125 antibody; FLJ27436 antibody; FLJ36714 antibody; hSOH1 antibody; MED31 antibody; mediator complex subunit 31 antibody; Mediator complex subunit SOH1 antibody; Soh1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MED31 recombinant protein (Accession Number: NM_016060). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
MED31, also named as SOH1 or CGI-125, is a 131 amino acid protein, which belongs to the Mediator complex subunit 31 family. MED31 localizes in the nucleus. MED31 as a component of the Mediator complex, a coactivator is involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED31 functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.

References :
Risley MD, Clowes C, Yu M, Mitchell K, Hentges KE. The Mediator complex protein Med31 is required for embryonic growth and cell proliferation during mammalian development. Developmental biology. 342(2):146-56. 2010.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel