Name :
mH2A2 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to mH2A2
Tested applications :
WB, FC
Species reactivity :
Human, Mouse
Alternative names :
H2AFY2 antibody; macroH2A2 antibody; core histone macro-H2A.2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide of human H2AFY2
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, pH7.3.
Storage instructions :
Store at 4℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000FC 1:20 – 1:50
Background :
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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