Name :
MIER3 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MIER3 Rabbit Polyclonal antibody. Positive WB detected in mouse uterus tissue. Observed molecular weight by Western-blot: 55kd
Tested applications :
ELISA, WB
Species reactivity :
human, mouse, rat; other species not tested.
Alternative names :
MIER3 antibody; FLJ35954 antibody; DKFZp781I1119 antibody; DKFZp781G1119 antibody; Mi er3 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MIER3 recombinant protein (Accession Number: XM_047416839). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
The mesoderm induction early response (MIER) protein family is known as fibroblast growth factor (FGF)-regulated immediate-early protein family. Activated by FGF, MIER proteins may have a pivotal role in FGF-regulated cellular activities, indicating a potential influence in the progression of certain cancers [PMID:15117948]. MIER3 localizes to the nucleus and primarily functions as a transcriptional repressor. Rat mammary carcinoma susceptibility 1b (Mcs1b) is a quantitative trait locus on RN02 that confers decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome. MIER3 is a candidate Mcs1b gene [PMID:22993404].
References :
Chen SW, Liu CC, Yen HC. Detection of suppressed maturation of the human COQ5 protein in the mitochondria following mitochondrial uncoupling by an antibody recognizing both precursor and mature forms of COQ5. Mitochondrion. 13(2):143-52. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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