Name :
MINA antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MINA Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in HEK-293 cells, A375 cells, mouse liver tissue. Positive IP detected in HEK-293 cells. Observed molecular weight by Western-blot: 53 kDa
Tested applications :
ELISA, WB, IHC, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
DKFZp762O1912 antibody; FLJ14393 antibody; MDIG antibody; MINA antibody; Mina53 antibody; MYC induced nuclear antigen antibody; NO52 antibody; Nucleolar protein 52 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MINA recombinant protein (Accession Number: XM_005247838). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200
Background :
MINA, also named as MDIG, MINA53 and NO52, belongs to the MINA53/NO66 family. It is involved in cellular proliferation. MINA may play an important role in cell growth and survival. It is involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. The transcriptional repressor MINA has been shown to repress Il4 gene expression by directly binding to its promoter, thereby, controlling TH2 bias.(PMID:21499227)
References :
Kashiwada M, Cassel SL, Colgan JD, Rothman PB. NFIL3/E4BP4 controls type 2 T helper cell cytokine expression. The EMBO journal. 30(10):2071-82. 2011.
Related websites: https://www.medchemexpress.com/antibodies.html
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