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Name :
MKL1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MKL1 Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human tonsillitis tissue, human liver cancer tissue, human small intestine tissue. Positive WB detected in HepG2 cells, HeLa cells. Observed molecular weight by Western-blot: 145 kDa

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human; other species not tested.

Alternative names :
BSAC antibody; KIAA1438 antibody; MAL antibody; MKL/myOCardin like protein 1 antibody; MKL1 antibody; MRTF A antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MKL1 recombinant protein (Accession Number: BC115039). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IHC: 1:20-1:200IF: 1:20-1:200

Background :
MKL1 represents megakaryoblastic leukemia (translocation) 1

References :
Shu XZ, Zhang LN, Zhang R. Histone acetyltransferase p300 promotes MRTF-A-mediates transactivation of VE-cadherin gene in human umbilical vein endothelial cells. Gene. 563(1):17-23. 2015. He H, Wang D, Yao H. Transcriptional factors p300 and MRTF-A synergistically enhance the expression of migration-related genes in MCF-7 breast cancer cells. Biochemical and biophysical research communications. 467(4):813-20. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel