Name :
MLLT10 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to MLLT10
Tested applications :
WB
Species reactivity :
Human, Mouse
Alternative names :
MLLT10 antibody; AF10 antibody; protein AF-10 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human MLLT10 (NP_001182555.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 ‘Lys-79’ dimethylation (H3K79me2) and gene activation.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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