Name :
MLN64 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MLN64 Rabbit Polyclonal antibody. Positive IP detected in MCF-7 cells. Positive WB detected in MCF7 cells, mouse brain tissue, mouse placenta tissue. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 48-53 kDa
Tested applications :
ELISA, WB, IHC, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
CAB1 antibody; MLN 64 antibody; MLN64 antibody; Protein CAB1 antibody; STARD3 antibody
Immunogen :
Human MLN64,STARD3 Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MLN64 recombinant protein (Accession Number: XM_047435165). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200
Background :
MLN64 (also known as STARD3) is an integral membrane protein anchored in late endosomes. MLN64 has a StAR-related lipid-transfer (START) domain to bind cholesterol, mediating intracellular cholesterol transfer. MLN64 is widely expressed in multiple tissues including liver, spleen, heart, kidney, lung, and the brain. Higher expression of MLN64 has been found in several malignancies.
References :
Liu R, Li J, Zhang T. Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking. Autophagy. 10(7):1241-55. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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