Name :
MMS19 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MMS19 Mouse Monoclonal antibody. Positive WB detected in Hepg2 cells, human brain tissue, human kidney tissue. Positive IP detected in mouse brain tissue. Positive IHC detected in human cervical cancer tissue. Positive IF detected in Hela cells. Observed molecular weight by Western-blot: 103 kDa,38 kDa
Tested applications :
ELISA, WB, IF, IHC, IP
Species reactivity :
Human, Mouse, Rat; other species not tested.
Alternative names :
FLJ34167 antibody; FLJ95146 antibody; hMMS19 antibody; MET18 antibody; MET18 homolog antibody; MMS19 antibody; MMS19 like protein antibody; MMS19L antibody
Immunogen :
Human MMS19 Recombinant protein (His tag)
Isotype :
Mouse IgG2b
Preparation :
This antibody was obtained by immunization of MMS19 recombinant protein (Accession Number: BC006575). Purification method: Protein A purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:1000-1:10000IHC: 1:20-1:200IF: 1:20-1:200
Background :
MMS19 (MMS19 nucleotide excision repair homolog), also known as MET18, is a 1,030 amino acid nuclear protein containing seven HEAT repeats that belongs to the MET18/MMS19 family. Via its interactions with TFIIH p80 and TFIIH p89 helicases, MMS19 plays a role in nucleotide excision repair (NER) and RNA polymerase II (Pol II) transcription. MMS19 may also function as a transcriptional coactivator of estrogen receptor. While ubiquitously expressed, highest levels of MMS19 have been found in testis. At least five distinct MMS19 protein isoforms exist, which are produced by alternative splicing events.
References :
Stehling O, Vashisht AA, Mascarenhas J. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. Science (New York, N.Y.). 337(6091):195-9. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
MUC16 Antibody (YA890) Technical Information
Crizanlizumab site
Jagged1 Antibody: Jagged1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 134 kDa, targeting to Jagged1. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.
